Opportunity Information: Apply for RFA RM 11 024
Apply for RFA RM 11 024
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Phased Economic Studies Ancillary to Planned Health Care Delivery and Financing Pilots, Demonstrations, and Other Experiments (R21/R33)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Oct 7, 2011 and posted on Oct 7, 2011.
- Applicants must submit their applications by Feb 8, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses City or township governments County governments Public and State controlled institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity RFA-RM-11-024, titled "Phased Economic Studies Ancillary to Planned Health Care Delivery and Financing Pilots, Demonstrations, and Other Experiments (R21/R33)," supports health economics research that is intentionally paired with real-world, large-scale health care delivery and financing pilots, demonstrations, and other experiments (often abbreviated as PDEs). The central idea is to fund economic studies that run alongside these planned policy or system changes, so researchers can generate credible evidence about whether the interventions actually reduce health care costs or slow cost growth while maintaining or improving patient outcomes. In practice, this means the economics work is not happening in isolation; it is designed to take advantage of an on-the-ground implementation effort that is already planned or underway, and to produce decision-relevant findings about spending, utilization, incentives, quality, and outcomes.
This announcement uses the NIH Phased Innovation grant structure, combining an R21 planning and feasibility phase with a potential transition to an R33 expanded research phase. The R21 phase can last up to two years and is meant for foundational work that makes the later, larger study possible and credible. Typical R21 activities would include refining the evaluation design; negotiating and securing access to data streams; building partnerships with the organizations running the pilot or demonstration; defining measures and outcomes; testing recruitment, survey instruments, or data linkage methods; and conducting feasibility analyses that reduce risk before scaling. If the project meets clearly defined and measurable milestones during the R21 period, it may transition to the R33 phase, which can provide up to four additional years of support for full implementation of the economic evaluation. Even though the two phases could add up to six years in theory, this FOA caps the total project period at five years, so applicants have to plan the timeline accordingly. A key feature is the milestone requirement: transition to R33 is not automatic, and applicants must specify objective R21 milestones that demonstrate readiness to execute the larger-scale research.
The research focus is explicitly on health economics and the economic consequences of health care reform-related interventions. While the FOA text in the summary does not list specific required topics, the emphasis is on rigorous economic evaluation conducted in the context of delivery and financing changes. That often includes assessing total cost of care, payer and patient spending, cost-effectiveness where appropriate, utilization patterns, provider behavior under new payment incentives, spillover effects, distributional impacts across populations, and links between spending changes and clinical or patient-centered outcomes. Because the studies are ancillary to pilots and demonstrations, strong applications would typically align the research questions, comparison groups, and measurement strategy with the timing and structure of the underlying PDE, using methods suited to policy evaluation (for example, quasi-experimental approaches when randomization is not feasible).
Administratively, this is a discretionary grant opportunity from NIH, categorized under health, with CFDA number 93.310 (Trans-NIH Research Support). It is part of the NIH Common Fund initiative "Health Economics for Health Care Reform," which signals an interest in cross-cutting evidence that can inform national discussions about delivery system change and cost containment. The posting date and creation date were October 7, 2011, and the original and current closing date listed is February 8, 2012, with an archive date of March 10, 2012, meaning this specific competition is historical rather than currently open. The listed award ceiling is $200,000, which typically indicates a cap on certain budget elements per year or per phase as specified in the full FOA; applicants would need to follow the detailed budget rules in the full announcement.
Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants include for-profit organizations (including small businesses), nonprofit organizations (including those with and without 501(c)(3) status), public and private institutions of higher education, state and local governments (city/township, county, special district), independent school districts, public housing authorities/Indian housing authorities, Native American tribal governments and tribal organizations, and various mission-focused institutions such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Regional organizations and U.S. territories or possessions are also included. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; foreign components (as NIH defines them) are not allowed.
For official details, applicants were directed to the full FOA page hosted by NIH, and NIH’s Office of Extramural Research webmaster contact was provided for access or technical linking issues. The summary information makes clear that proposals were expected to be tightly organized around a phased plan: first proving feasibility and completing pre-specified milestones in the R21 period, then moving into a more definitive, larger-scale economic study in the R33 period that leverages a real delivery or financing experiment to produce policy-relevant evidence on costs and outcomes.
Frequently Asked Questions (FAQs)
What is the NIH funding opportunity RFA-RM-11-024 about?
RFA-RM-11-024, titled "Phased Economic Studies Ancillary to Planned Health Care Delivery and Financing Pilots, Demonstrations, and Other Experiments (R21/R33)," supports health economics research designed to run alongside real-world, large-scale health care delivery and financing pilots, demonstrations, and other experiments (often called PDEs). The goal is to generate credible, decision-relevant evidence about whether these interventions reduce health care costs or slow cost growth while maintaining or improving patient outcomes.
What does it mean that the economic study must be "ancillary" to a pilot, demonstration, or experiment?
It means the economics research is intentionally paired with, and takes advantage of, an on-the-ground implementation effort that is already planned or underway. The study is not conducted in isolation; it is designed around the timing, structure, and operational realities of the underlying health care delivery or financing change.
What kinds of underlying projects qualify as PDEs in this announcement?
The opportunity is oriented to planned health care delivery and financing pilots, demonstrations, and other experiments implemented in real-world settings and at meaningful scale. The summary information refers to these broadly as PDEs without listing specific required models.
What is the main research purpose of these ancillary economic studies?
The central purpose is to assess the economic consequences of health care reform-related interventions, with a particular focus on whether delivery and financing changes influence spending and utilization while maintaining or improving quality and outcomes. The expected product is evidence that is credible and relevant to policy and operational decision-making.
What grant mechanism is used (R21/R33), and what does "phased" mean?
This FOA uses the NIH Phased Innovation structure, combining an R21 planning and feasibility phase with a potential transition to an R33 expanded research phase. "Phased" means the project is intentionally split into two stages: first to prove feasibility and readiness, and then (only if milestones are met) to carry out the larger-scale evaluation.
How long can the R21 phase last, and what is it intended to support?
The R21 phase can last up to two years. It supports foundational work needed to make the later economic evaluation possible and credible, such as refining the evaluation design, securing data access, formalizing partnerships with PDE operators, defining measures and outcomes, testing recruitment or survey instruments, piloting data linkage, and performing feasibility analyses.
How long can the R33 phase last, and what is it intended to support?
If the project meets clearly defined and measurable R21 milestones, it may transition to the R33 phase for up to four additional years. The R33 phase supports full implementation of the expanded economic evaluation aligned with the real-world pilot or demonstration.
What is the maximum total project period under this FOA?
Although the R21 (up to 2 years) plus R33 (up to 4 years) could total six years in theory, this FOA caps the total project period at five years. Applicants must plan the timeline so the combined R21 and R33 activities fit within five years.
Is transition from R21 to R33 automatic?
No. Transition to the R33 phase is not automatic. The R21 phase must achieve objective, pre-specified milestones that demonstrate readiness to execute the larger-scale research.
What are R21 milestones, and how are they used in this FOA?
Milestones are clearly defined, measurable goals set for the R21 feasibility period. They are used to determine whether the project is ready to move into the R33 phase. Applicants are expected to specify objective milestones that demonstrate feasibility and readiness for full implementation.
What types of activities are examples of appropriate R21 milestone-driven work?
Examples mentioned in the opportunity summary include refining the evaluation design; negotiating and securing access to data streams; building partnerships with organizations running the pilot or demonstration; defining measures and outcomes; testing recruitment, survey instruments, or data linkage methods; and conducting feasibility analyses that reduce risk before scaling.
What research topics and outcomes are emphasized?
The emphasis is on rigorous health economics evaluation in the context of delivery and financing changes. Typical areas include total cost of care; payer and patient spending; utilization patterns; provider behavior under new payment incentives; spillover effects; distributional impacts across populations; cost-effectiveness where appropriate; and connections between spending changes and clinical or patient-centered outcomes.
Does the summary list specific required topics?
No specific required topics are listed in the summary information provided. The focus is described broadly as health economics and the economic consequences of health care reform-related interventions, evaluated in conjunction with real-world delivery and financing experiments.
What kinds of evaluation methods are suggested or implied?
The summary emphasizes alignment with the timing and structure of the underlying PDE and methods suited to policy evaluation. It notes that quasi-experimental approaches may be appropriate when randomization is not feasible, and highlights the importance of credible comparison groups and measurement strategies matched to the PDE.
How important is alignment with the underlying pilot or demonstration timeline?
It is central. Because the economic study is designed to run alongside a planned or underway PDE, strong applications would typically align research questions, comparison groups, and measurement strategies with how and when the underlying delivery or financing change is implemented.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.310, described as Trans-NIH Research Support.
How is this opportunity categorized administratively?
It is described as a discretionary NIH grant opportunity categorized under health, and it is associated with a NIH Common Fund initiative.
What NIH initiative is this opportunity part of?
The opportunity is part of the NIH Common Fund initiative "Health Economics for Health Care Reform," indicating interest in cross-cutting evidence to inform national discussions on delivery system change and cost containment.
What is the listed award ceiling?
The listed award ceiling is $200,000. The summary notes that this typically indicates a cap on certain budget elements per year or per phase as specified in the full FOA, and applicants would need to follow the detailed budget rules in the full announcement.
Is this funding opportunity currently open?
No. The posting/creation date is October 7, 2011, the original and current closing date listed is February 8, 2012, and the archive date is March 10, 2012. Based on these dates, this specific competition is historical rather than currently open.
Who is eligible to apply?
Eligibility is broad for U.S.-based organizations and governmental entities. Eligible applicants include for-profit organizations (including small businesses), nonprofit organizations (with and without 501(c)(3) status), public and private institutions of higher education, and a wide range of government entities and mission-focused institutions.
Are state and local government entities eligible?
Yes. The summary includes state and local governments, including city/township governments, county governments, and special district governments. It also lists independent school districts and public housing authorities/Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. Native American tribal governments and Native American tribal organizations are listed as eligible applicant types.
Are specific minority-serving institutions included as eligible applicants?
Yes. The summary lists multiple mission-focused institution types as eligible, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, and others.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly included in the eligibility list.
Are U.S. territories or possessions eligible to apply?
Yes. The summary indicates that U.S. territories or possessions are included among eligible applicants.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this opportunity.
Can a U.S. organization include non-U.S. components or foreign components in the project?
No. The summary states that non-U.S. components of U.S. organizations are not eligible, and that foreign components (as NIH defines them) are not allowed.
Where were applicants directed for official details and requirements?
Applicants were directed to the full FOA page hosted by NIH for official details. The NIH Office of Extramural Research webmaster contact was provided for access or technical linking issues.
What does NIH expect proposals to be organized around?
The summary indicates proposals were expected to be tightly organized around a phased plan: completing feasibility work and pre-specified milestones in the R21 period, then moving into a more definitive and larger-scale economic study in the R33 period that leverages the real delivery or financing experiment to produce policy-relevant evidence on costs and outcomes.
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